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Recursion, Bayer Expand Fibrosis Pact To Include Inferential Search Capabilities
Monday, December 6, 2021 - 1:44pm | 226Recursion Pharmaceuticals Inc (NASDAQ: RXRX) expanded its existing strategic collaboration in fibrosis with Bayer AG (OTC: BAYRY). The expanded collaboration will include Recursion's inferential search capabilities based on its growing maps of human cellular...
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Galmed's NASH Candidate Shows Clinically Significant Effect On Fibrosis Improvement
Monday, November 8, 2021 - 1:53pm | 262Galmed Pharmaceuticals Ltd (NASDAQ: GLMD) has announced histology and biomarkers analysis results from the Ongoing Open-Label Part of the ARMOR Phase 3 study of Aramchol in NASH and liver fibrosis stage 1 3 patients. Galmed previously announced a substantial effect on ...
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Angion Biomedica Shares Moving Higher On Encouraging Results From Early Stage Trial Of Fibrotic Disease Candidate
Tuesday, August 3, 2021 - 9:31am | 274Angion Biomedica Corp (NASDAQ: ANGN) has announced positive results from its Phase 1 study in healthy volunteers for ANG-3070 for fibrotic diseases. In the 97-volunteer trial, ANG-3070 achieved drug exposures in humans exceeding exposures in which activity was demonstrated in...
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Galecto's GB0139 Shows Favorable Safety In COVID-19 Patients, But Plans To Focus On Fibrosis, Cancer Programs
Tuesday, June 22, 2021 - 12:40pm | 220Amid the continued evolution of the COVID-19 landscape, Galecto Inc (NASDAQ: GLTO) said it would focus on the Phase 2 pipeline of fibrosis and cancer treatments, despite announcing positive preliminary topline results from an investigator-initiated trial examining GB0139 in...
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Corbus In-Licenses Two Anti-Integrin Antibodies Targeting Cancer, Fibrotic Diseases Settings
Tuesday, June 1, 2021 - 12:26pm | 244Corbus Pharmaceuticals Holdings Inc (NASDAQ: CRBP) has announced licensing deals for two new monoclonal antibodies (mAbs), CRB-601 and CRB-602, that target integrins to inhibit activation of transforming growth factor β (TGFβ). TGFβ is a multifunctional cytokine...
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Liminal BioSciences Stock Falls on Scrapping Further Development of Fezagepras
Tuesday, June 1, 2021 - 8:07am | 169Based on interim pharmacokinetics (PK) results from the ongoing multiple ascending dose study Liminal BioSciences Inc (NASDAQ: LMNL) has decided not to move fezagepras into a Phase 2 study in Idiopathic Pulmonary Fibrosis and a Phase 1a/2b study in Hypertriglyceridemia. The Company...
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Arrowhead's ARO-AAT Treatment Associated With Improved Fibrosis In Patients With Alpha-1 Liver Disease
Wednesday, April 28, 2021 - 11:47am | 375Arrowhead Pharmaceuticals Inc (NASDAQ: ARWR) has announced positive interim 48-week liver biopsy results from the Phase 2 AROAAT2002 study evaluating ARO-AAT for rare genetic liver disease associated with alpha-1 antitrypsin deficiency (AATD). AATD is the lack of a...
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Hepion Pharmaceutical's Lead Drug Shows Antifibrotic Effects In Animal Studies
Tuesday, March 23, 2021 - 11:10am | 170Hepion Pharmaceuticals Inc (NASDAQ: HEPA) has announced positive results from an in vivo study of CRV431. In this study, the mouse model was treated for eight weeks with oral dosing of CRV431, or two comparator drugs, obeticholic acid, and elafibranor. Fibrosis was...
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aTyr Pharma Gains On New Programs From tRNA Synthetase Platform For Cancer Targets
Thursday, February 11, 2021 - 11:34am | 202aTyr Pharma Inc (NASDAQ: LIFE) has initiated two discovery programs from its tRNA synthetase platform that will investigate the functionality of selected fragments of Alanyl-tRNA Synthetase (AARS) and Aspartyl-tRNA Synthetase (DARS) in immunology, fibrosis, and cancer. The...