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Innate Pharma Says Chemo-Free Monalizumab Triplet Therapy Shows Preliminary Anti-Cancer Activity
Thursday, December 9, 2021 - 10:28am | 305Innate Pharma SA's (NASDAQ: IPHA) data from the Phase 2 expansion cohort (cohort 3) evaluating the monalizumab triplet combination shows preliminary activity and an acceptable safety profile with a low discontinuation rate. Cohort 3 is exploring the triplet combination of...
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Why Did Galera Therapeutics Shares Plunge To All Time Lows Today?
Tuesday, October 19, 2021 - 8:32am | 288Galera Therapeutics Inc (NASDAQ: GRTX) stock has plunged to all-time since its listing in November 2019 in reaction to disappointing data from the Phase 3 ROMAN trial of avasopasem manganese in severe oral mucositis (SOM) patients with locally advanced head and neck cancer (HNC)...
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Hookipa Pharma, Merck Team Up For Phase 2 Head & Neck Cancer Trial
Wednesday, September 15, 2021 - 8:43am | 249Hookipa Pharma Inc (NASDAQ: HOOK) has entered into a clinical collaboration and supply agreement with Merck & Co Inc (NYSE: MRK). The collaboration will evaluate the combination of HB-200 and Keytruda (pembrolizumab) as first-line treatment of advanced head and neck...
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Junshi Biosciences, Coherus Receive FDA Breakthrough Therapy Status For Toripalimab In Head & Neck Cancer
Thursday, August 12, 2021 - 9:10am | 197The FDA has granted Breakthrough Therapy Designation (BTD) to Shanghai Junshi Biosciences Co Ltd - Coherus BioSciences Inc's (NASDAQ: CHRS) toripalimab for recurrent or metastatic nasopharyngeal carcinoma (NPC). NPC is a rare tumor of the head and neck. The...
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Bristol-Myers' Opdvio/Yervoy Combo Therapy Flunks In Head & Neck Cancer Trial
Friday, July 16, 2021 - 8:05am | 202Bristol Myers Squibb & Co's (NYSE: BMY) Phase 3 CheckMate -651 data evaluating Opdivo (nivolumab) plus Yervoy (ipilimumab) combo in head and neck cancer failed to primary endpoints of the trial. The trial assessed Opdivo plus Yervoy combination to Extreme regimen (cetuximab...
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Galectin Therapeutics Stock Surges After Robust Data From Belapectin/Keytruda Combo In Melanoma, Head & Neck Cancer
Friday, July 9, 2021 - 9:25am | 260Galectin Therapeutics Inc (NASDAQ: GALT) has announced top-line clinical data from the extension cohort of Phase 1b trial of Belapectin in combination with Merck & Co Inc's (NYSE: MRK) Keytruda (pembrolizumab) in patients with metastatic melanoma and head &...
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Immutep Shares Are Trading Higher On Green Signal To Start Efti Combo Trial In First-Line Head & Neck Cancer
Tuesday, July 6, 2021 - 7:20am | 258Immutep Limited (NASDAQ: IMMP) has completed all the necessary steps with the FDA and has received institutional review board approval to commence its Phase 2b TACTI-003 trials in the U.S. Patient recruitment for the trial will begin in Q3 of 2021. It will evaluate the Company's...
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CEL-SCI's Immunotherapy Achieves Survival Benefit Of 14% Exceeding Pre-Defined 10% In Head & Cancer Patients
Monday, June 28, 2021 - 9:46am | 226CEL-SCI Corporation (NYSE: CVM) has announced results from its Phase 3 study for its immunotherapy Multikine for advanced previously untreated squamous cell carcinoma of the head and neck (SCCHN). In the intent to treat patients, the study showed a statistically significant overall...
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Vaccinex Initiates Pepinemab Trials for Alzheimer's, Head & Neck Cancer
Tuesday, June 8, 2021 - 7:57am | 211Vaccinex Inc (NASDAQ: VCNX) has activated first clinical sites to screen and enroll patients in its Phase 1/2 study evaluating pepinemab as a single agent in Alzheimer's disease (AD) and in its phase 2 study in combination with Merck & Co Inc's (NYSE: MRK)...
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Nanobiotix's Nanoparticle Technology Shows Tumor-Killing Effect in Early-Stage Head & Neck Cancer
Friday, June 4, 2021 - 9:34am | 265Nanobiotix (NASDAQ: NBTX), ahead of the 2021 Annual Meeting of the American Society for Clinical Oncology meeting, has said that its nanoparticles were able to shrink tumors in about 77% of patients in a small Phase 1 trial. NBTXR3 consists of crystalline nanoparticles that are delivered...
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BeiGene's Tislelizumab Shows Progression-Free Survival Benefit in Type Of Head & Neck Cancer
Friday, May 21, 2021 - 8:21am | 205BeiGene Ltd (NASDAQ: BGNE) has announced topline results from the Phase 3 RATIONALE 309 trial evaluating tislelizumab combined with chemotherapy as a first-line treatment of recurrent or metastatic nasopharyngeal cancer, a rare type of head and neck cancer. The trial...
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Cue Biopharma's Stock Shoots Up After CUE-101 Shows Promise In Early-Stage Head & Neck Cancer Study
Monday, May 10, 2021 - 1:14pm | 308Cue Biopharma Inc (NASDAQ: CUE) has announced interim clinical data from its ongoing Phase 1a/1b monotherapy study of CUE-101 as second-line treatment for patients with human papilloma virus-positive recurrent/metastatic head and neck squamous cell carcinoma (HPV+ R/M HNSCC)....
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IsoRay's Cesium-131 And Surgical Resection Shows Promise In Recurrent Head & Neck Cancer
Wednesday, March 31, 2021 - 10:12am | 281According to a recently published small pilot study of patients with recurrent head and neck cancers treated with surgical resection and IsoRay Inc's (NYSE: ISR), Cesium-131 brachytherapy showed potential benefits that could support further research into combination...
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Immutep's Lead Candidate To Be Tested In Combination With Keytruda In Second Head & Neck Cancer Study
Tuesday, March 16, 2021 - 9:15am | 236Immutep (NASDAQ: IMMP) announces a second clinical trial collaboration and supply agreement with Merck & Co Inc (NYSE: MRK). Under the agreement, Immutep will conduct a new Phase 2B clinical trial in 1st line head and neck squamous cell carcinoma (HNSCC) patients...
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Kura Oncology Receives FDA Breakthrough Therapy Tag For Tipifarnib In Head & Neck Cancer
Wednesday, February 24, 2021 - 10:12am | 177The FDA has designated Breakthrough Therapy status to Kura Oncology Inc's (NASDAQ: KURA) tipifarnib, an orally bioavailable inhibitor of farnesyl transferase for head and neck cancer. The status covers recurrent or metastatic HRAS mutant head and neck squamous cell...