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BWXT Medical, Bayer AG Ink Agreement On Actinium-225
Thursday, September 16, 2021 - 10:24am | 226BWX Technologies Inc's (NYSE: BWXT) subsidiary BWXT Medical Ltd. has agreed with Bayer AG (OTC: BAYRY) to develop Actinium-225 (Ac-225) supply and further partnering opportunities on finished products. The financial terms of the agreement were not disclosed. The...
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Merck's Belzutifan Wins FDA Approval As First Drug For Rare VHL Tumors
Monday, August 16, 2021 - 6:23am | 305The FDA on Friday approved Merck & Co Inc's (NYSE: MRK) belzutifan for patients with the rare disorder known as von Hippel-Lindau (VHL) disease. VHL is a rare genetic disease that causes tumors and cysts to grow throughout the body. Belzutifan was one of the most...
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Epizyme Stock Gains On Potential $310M Pact With HUTCHMED For Cancer-Focused Tazverik In Greater China
Monday, August 9, 2021 - 6:15am | 276Epizyme Inc (NASDAQ: EPZM) and HUTCHMED (China) Limited (NASDAQ: HCM) have collaborated to research, develop, manufacture, and commercialize Tazverik (tazemetostat) in Greater China, including mainland China, Hong Kong, Macau, and Taiwan. Tazverik is a methyltransferase...
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Auris Medical Stock Trading Higher After OligoPhore Technology Shows Tumor Inhibition In Animal Studies
Monday, June 21, 2021 - 10:28am | 232Auris Medical Holding Ltd (NASDAQ: EARS) has announced the publication of positive results from an in vivo study employing its OligoPhore technology in Adult T-cell Leukemia-Lymphoma (ATLL). The article was published in Nanomaterials, an international peer-reviewed open-access...
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Novartis' Neuroendocrine Tumors Targeted Radiotherapy Takes Small Hit on Clinically Relevant Overall Survival
Friday, June 4, 2021 - 3:10pm | 341Novartis AG (NYSE: NVS) reported the final analysis from the NETTER-1 phase 3 study comparing Lutathera plus 30 mg Sandostatin LAR (octreotide) to 60 mg octreotide LAR in patients with midgut neuroendocrine tumors. Lutathera failed to significantly prolong the lives of patients with...
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Oric Pharma's ORIC-101 Shows Tumor Regression, Prolonged Stable Disease in Multiple Heavily Pretreated Tumors
Thursday, June 3, 2021 - 8:22am | 283Oric Pharmaceuticals Inc (NASDAQ: ORIC) has announced initial data from an ongoing Phase 1b study evaluating ORIC-101 in combination with nab-paclitaxel, in advanced solid tumors. Data will be presented at the American Society of Clinical Oncology (ASCO) Annual Meeting. As of the...
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Phio Pharma's PH-762 Shows Encouraging Antitumor Efficacy In Preclinical Studies
Tuesday, May 11, 2021 - 1:10pm | 240Phio Pharmaceuticals Corp (NASDAQ: PHIO) stock falls despite the company announcing positive new in vivo data showing that PH-762 significantly enhanced the antitumor efficacy of HER2-targeted CAR-T cells (HER2CART) in solid tumors. Compared to untreated, HER2CART cells treated...
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Adaptimmune's HiT Program Can Potentially Kill Human Tumor Cells, Animal Study Shows
Tuesday, May 11, 2021 - 12:32pm | 226Adaptimmune Therapeutics plc (NASDAQ: ADAP) has reported first preclinical data from its HiT targeting mesothelin (a tumor-associated antigen), being co-developed with Astellas Pharma (OTCMKTS: ALPMF) The data were presented at the American Society for Cell and Gene...
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FDA Oncology Adcomm Votes To Keep Conditional Approval For Roche's Tecentriq In Place For Now
Wednesday, April 28, 2021 - 9:16am | 365The FDA kicked off a three-day meet to reexamine the accelerated approvals of immuno-oncology drugs with confirmatory trials that have not met their primary endpoint(s) and have yet to gain regular approvals. FDA’s Oncologic Drugs Advisory Committee (ODAC) started the meet with Roche...
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Hoth Therapeutics' mRNA Frame Shifting Therapeutic Inhibits Tumor Growth, Animal Study Shows
Tuesday, April 20, 2021 - 2:07pm | 186Hoth Therapeutics Inc (NASDAQ: HOTH) has reported that its novel anti-cancer therapeutic demonstrated positive results in humanized mast-cell neoplasm animal models for aggressive, mast cell-derived cancers such as mast cell leukemia and mast cell sarcoma. The anti-cancer...
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Phio Pharma's Intasyl Platform Shows Promising Tumor Control Activity In Animal Studies
Monday, April 12, 2021 - 7:33am | 271Phio Pharmaceuticals Corp (NASDAQ: PHIO) announced new preclinical data for the Intasyl platform in tumor settings. These data were presented today during the AACR Annual Meeting 2021. Data showed that local intratumoral (IT) delivery with the murine PD-1 targeting Intasyl (mPH...
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Compugen To Test COM701, Opdivo Combination In Solid Tumor Settings
Monday, February 22, 2021 - 2:58pm | 209Compugen Ltd (NASDAQ: CGEN) expands its clinical collaboration agreement with Bristol-Myers Squibb Co (NYSE: BMY), wherein Bristol Myers will supply Opdivo (nivolumab) for Compugen's Phase 1b cohort expansion study evaluating COM701, anti-PVRIG antibody. The...
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Theratechnologies' Peptide Conjugate Candidate For Solid Tumor Nabs Priority Review Tag In US, Shares Rally
Thursday, February 4, 2021 - 9:24am | 260The FDA has designated Fast Track status to Theratechnologies Inc's (NASDAQ: THTX) TH1902 as a single agent for treating patients with sortilin positive recurrent advanced solid tumors that are refractory to standard therapy. Last month, the FDA signed off Phase 1...
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Goldman Confident In Merck's Keytruda
Tuesday, June 7, 2016 - 2:43pm | 288Goldman Sachs said evidence of Merck & Co., Inc. (NYSE: MRK)'s Keytruda benefit as a single agent continues to build as registrational monotherapy studies read out. Merck's data presented at ASCO (American Society of Clinical Oncology) include updates on new tumors, existing tumors and...